Gotham's Most Wanted

Gotham's Most Wanted are side missions that are featured in the Batman: Arkham series.

In Arkham Asylum, Arkham City, and Arkham Origins, they are optional. In Arkham Knight, all the Most Wanted missions (except the ones from The Season of Infamy) are required to unlock The Knightfall Protocol 100% ending.

Batman: Arkham Origins

 * Enigma
 * Anarky
 * Penguin
 * Mad Hatter
 * Shiva
 * Deadshot
 * Black Mask
 * Bird
 * Blackgate Prisoners

Batman: Arkham Asylum

 * Riddler

Batman: Arkham City

 * Acts of Violence (Political Prisoners)
 * Watcher in the Wings (Azrael)
 * Cold Call Killer (Victor Zsasz)
 * Fragile Alliance (Bane)
 * AR Training (Prototype Grapnel Boost)
 * Shot in the Dark (Deadshot)
 * Enigma Conundrum (Riddler)
 * Identity Theft (Hush)
 * Remote Hideaway (Remote Mine Detonator)
 * The Tea Party (Mad Hatter)
 * Heart of Ice (Nora Fries)
 * Hot And Cold (Freeze Cluster Grenade)

Batman: Arkham Knight

 * City of Fear (Scarecrow - serves as the Main Story)
 * The Line of Duty (Station 17 Fire Crew)
 * The Perfect Crime (Professor Pyg)
 * Riddler's Revenge (Riddler)
 * Own The Roads (Militia Checkpoints)
 * Occupy Gotham (Militia Watchtowers)
 * Wonderland (Mad Hatter - requires The Season of Infamy DLC)
 * Campaign for Disarmament (Militia Bombs/Deathstroke)
 * Creature of the Night (Man-Bat)
 * Shadow War (Ra's al Ghul - requires The Season of Infamy DLC)
 * Heir to the Cowl (Azrael)
 * Gotham on Fire (Firefly)
 * Armored and Dangerous (APC Lieutenants)
 * Beneath the Surface (Killer Croc - requires The Season of Infamy DLC)
 * Gunrunner (Penguin)
 * Two-Faced Bandit (Two-Face)
 * In From the Cold (Mr. Freeze - requires The Season of Infamy DLC)
 * Friend in Need (Hush)
 * Lamb to the Slaughter (Deacon Blackfire)

Trivia

 * As of Knight, the Riddler is the only villain to have a Most Wanted mission in every Batman: Arkham game.